Mycotoxins are some of the most prevalent toxins in the environment. Mycotoxins are metabolites produced by fungi like mold, which can infest buildings, vehicles, and foodstuffs. A majority of mycotoxin exposures are through food ingestion or airborne exposure. Unfortunately, mycotoxins are resistant to heat and many processing procedures. Fungi are able to grow on almost any surface, especially if the environment is warm and wet. Inner wall materials of buildings, wall paper, fiber glass insulation, ceiling tiles, and gypsum support are all good surfaces for fungi to colonize.
These fungi then release mycotoxins into the environment causing symptoms of many different chronic diseases. Diseases and symptoms linked to mycotoxin exposure include fever, pneumonia-like symptoms, heart disease, rheumatic disease, asthma, sinusitis, cancer, memory loss, vision loss, chronic fatigue, skin rashes, depression, ADHD, anxiety, and liver damage.
Aflatoxin M1 AFM1 is the main metabolite of aflatoxin B1, which is a mycotoxin produced by the mold species Aspergillus. Aflatoxins are some of the most carcinogenic substances in the environment.
Aflatoxin susceptibility is dependent on multiple different factors such as age, sex, and diet. Aflatoxin can be found in beans, corn, rice, tree nuts, wheat, milk, eggs, and meat. In cases of lung aspergilloma, aflatoxin has been found in human tissue specimens. Aflatoxin can cause liver damage, cancer, mental impairment, abdominal pain, hemorrhaging, coma, and death. Aflatoxin has been shown to inhibit leucocyte proliferation. Clinical signs of aflatoxicosis are non-pruritic macular rash, headache, gastrointestinal dysfunction often extremelower extremity edema, anemia, and jaundice.
The toxicity of Aflatoxin is increased in the presence of Ochratoxin and Zearalenone. Ochratoxin A OTA is a nephrotoxic, immunotoxic, and carcinogenic mycotoxin. This chemical is produced by molds in the Aspergillus and Penicillium families.
Exposure is primarily through contaminated foods such as cereals, grape juices, dairy, spices, wine, dried vine fruit, and coffee. Exposure to OTA can also come from inhalation exposure in water-damaged buildings. OTA can lead to kidney disease and adverse neurological effects.
Studies have shown that OTA can cause significant oxidative damage to multiple brain regions and the kidneys. Dopamine levels in the brain of mice have been shown to be decreased after exposure to OTA. Sterigmatocystin STG is a mycotoxin that is closely related to aflatoxin. It is considered to be carcinogenic, particularly in the cells of the GI tract and liver. STG has been found in the dust from damp carpets. It is also a contaminant of many foods including grains, corn, bread, cheese, spices, coffee beans, soybeans, pistachio nuts, and animal feed.
In cases of lung aspergilloma, STG has been found in human tissue specimens. The toxicity of STG affects the liver, kidneys, and immune system. Tumors have been found in the lungs of rodents that were exposed to STG.
Oxidative stress becomes measurably elevated during STG exposure, which causes a depletion of antioxidants such as glutathione, particularly in the liver.
Roridin E is a macrocyclic trichothecene produced by the mold species Fusarium, Myrothecium, and Stachybotrys i. Trichothecenes are frequently found in buildings with water damage but can also be found in contaminated grain.
This is a very toxic compound, which inhibits protein biosynthesis by preventing peptidyl transferase activity. Trichothecenes are considered extremely toxic and have been used as biological warfare agents.The efficient solution for multi-mycotoxin testing. The fast and reliable solution for on-site mycotoxin testing.
Increased concern for food and feed safety have brought mycotoxins to the spotlight and with that, the need for reliable and efficient mycotoxin screening. With over 30 years of experience in this field, Romer Labs offers the most comprehensive portfolio of mycotoxin test kits for the detection of regulated mycotoxins aflatoxinochratoxinfumonisindeoxynivalenolzearalenonet-2 and ht-2 in agricultural commodities such as raw grains and nuts, grain by-products and feed formulations.
Romer Labs test kits are validated for a wide range of agricultural raw materials, by-products and feed formulations. For individual commodities and feed formulations, you will find extensive support through our technical service departments across the world. The quality of the antibody is crucial for the quality of the test result. Romer Labs has a broad range of monoclonal and polyclonal antibodies, which are highly specific to the respective analyte and guarantee robust and accurate results.
The test kits are available in a qualitative or quantitative format.
Mycotoxin Urine Test
A complete overview can be found below. Click on the item number for more information. These ELISA test kits are the ideal solution for a parallel measurement of multiple samples with incubation times of as low as 15 minutes for up to 42 samples.
Test kits are in a ready-to-use format to reduce handling errors and come with a set of 5 standards, an antibody coated plate, a dilution plate, a conjugate, a substrate and a stop solution.
Contact us now! Knowledge Center Online Shop. Straight from his new home studio, Josh talks about different molds that are able to produce the same mycotoxin. Aflatoxins: highly regulated, very dangerous, and popping up in corn samples in the US.
Romer Labs provides the following test kits for the detection of mycotoxins:. Extensive technical service and support. Item No. Quantitation Range Limit of Detection No. Looking for more information? Related Media. Contact Romer Labs.There are several types of ochratoxin, but the type that is most commonly found in foods and is the most dangerous in terms of toxicity is ochratoxin A.
Is Mycotoxin Urine Testing Worthwhile?
Ochratoxin A infects a wide variety of foods both raw and processed. Ochratoxin contamination has been found in dried foods including nuts, beans, fruit and fish. It can infect wheat and barley crops, and it has also been found in poultry and pork. Symptoms of ochratoxin include listlessness, diarrhea, and tremors. In animals, it is linked to kidney damage and failure. Pigs are especially vulnerable to ochratoxin and are the most common carrier. It is also linked to kidney as well as liver damage in humans, who can contract the infection through tainted meat and grains.
Ochratoxin is stored in the liver for 35 days or more. At high levels, ochratoxin is categorized as a carcinogen, a cancer-causing agent, which eventually leads to the development of tumors in the kidneys. At higher levels of contamination, ochratoxin can cause neural damage, birth defects, and severe damage to the immune system.
Ochratoxin is particularly important to identify in storage because it is fat soluble. Any animals consuming grains contaminated with ochratoxin, especially swine and poultry, will store and accumulate the toxin in their fat, which could eventually find its way into the food and feed supply if not detected.
Penicillium verrucosum and Aspergillus ochraceus are more likely to contaminate foods in storage than they are to infect plants in the field, which means one of the best ways to prevent high levels of ochratoxin from developing in food is proper storage.
The likelihood of prevention is increased by keeping moisture levels low in storage facilities either by harvesting foods at a safe moisture level or immediately drying them to a safe moisture level after harvest. Testing for ochratoxin provides assurance about freedom from infection, whether in storage or the field.
Farmers, ranchers, grain millsgrain handlers and producers of animal feed should test for ochratoxin. Temperature can have a meaningful effect on ochratoxin. The optimal temperature for growth is between degrees fahrenheit depending on the level of humidity. Higher levels are usually detected in raw foods than in processed foods. Roasting and baking can decrease the potency of ochratoxin in some foods.VICAM's portfolio of quantitative strip tests, which are used in conjunction with the VICAM Vertu Lateral Flow Reader, provide validated monitoring solutions for companies seeking to minimize the costly consequences of mycotoxin contamination.
The tests can be easily performed on-site or in the lab, require no special training and have a long shelf life. Screen, quantify, and confirm mycotoxin levels with total confidence. Afla-V strip tests accurately detect and measure total aflatoxins B1, B2, G1, and G2 at levels as low as 2 ppb and as high as ppb. Accurately detect and measure total aflatoxins B1, B2, G1 and G2 at levels as low as 2.
Eliminate the need for hazardous solvents using a water-based, dilution-free extraction procedure. Fumo-V test strips accurately detect and measure total fumonisin B1, B2, and B3 at levels as low as 0.
The single dilution sample preparation procedure saves time and materials, and the test strip develops in just 5 minutes. Accurately detect and measure total fumonisin B1, B2 and B3 levels as low as 0. Eliminate the need for hazardous solvents using a water-based dilution-free extraction procedure.
Afla-V Afla-V strip tests accurately detect and measure total aflatoxins B1, B2, G1, and G2 at levels as low as 2 ppb and as high as ppb.The next generation in mycotoxin testing technology is the new QuickTox Flex product line. Using the QuickScan reader platform, QuickTox Flex mycotoxin tests utilize a simple, compact strip incubator to tightly control external variables such as temperature and humidity.
The dual-action incubator heats or cools the sample to optimal assay conditions, which guarantees repeatable testing conditions. Repeatable, reliable results are key to trusting a mycotoxin testing method.
The EnviroLogix range of mycotoxin testing kits are suitable for wheat, corn, rice, soybean, as well as water quality sampling for waste water, rivers and streams. Edaphic Scientific is the exclusive distributor of the EnviroLogix range of mycotoxin testing kits for Australia. They have been linked to a variety of health effects in humans and animals. When mycotoxins enter the food supply, they can wreak havoc at every point along the chain—affecting everyone from farmers to grain mills to consumers of the grain.
The grain supply is particularly susceptible because grains can become contaminated with mycotoxins during crop growth or during grain storage, establishing a need to test for mycotoxins at every stage in the food supply chain. Among veterinarians and feed and animal producers, mycotoxins are well known to affect the health and development of chickens, cows, horses and other animals who eat moldy grains. In the medical community, the effects of mycotoxins on humans are increasingly gaining attention, including in discussions related to gluten sensitivity.
Symptoms of chronic mycotoxin consumption vary from a weakening of the immune system to liver cancer. In most nations, mycotoxin prevalence in grains is regulated to protect citizens and production animals that consume the grain. Mycotoxin testing of grains is vital to ensure a healthy population of citizens and production animals.
Contamination of this scale has serious consequences. Quality assurance provides the foundation for a healthy, productive and profitable grain supply. To this end, numerous national and international government bodies regulate the quality of the grain supply. They also require stringent certification for the technology and test kits used to test for mycotoxins. Learn more about mycotoxin test certifications here. Quick, accurate mycotoxin testing can make all the difference when screening for food safety of grain.
Only with proven and certified technology can users make objective, real-time decisions that meet regulation standards and mitigate the risks of lost productivity and health due to mycotoxin infections. QuickScan Advanced, robust and precise reader for mycotoxin testing.Depending on specific substances and concentration, they are cancerogenic, mutagenic, teratogenic and immunosuppressive. The main source for mycotoxins entering the food chain are cereals, but many other food items such as fruits and nuts may be contaminated with mycotoxins as well.
Out of the approximately known species of mycotoxins, which belong to very different chemical compound classes, about 25 are counted as being relevant, due to their frequency in occurrence and their concentration. Is your product toxicologically safe and in compliance with all legal requirements? As the global leader for mycotoxin analysis, we offer to examine a large number of mycotoxins in a great variety of food and feed. Eurofins offers a variety of analyses, including testing for aflatoxins, ochratoxin A, fusarium toxins, alternaria toxins, patulin, penicillium toxins, ergot alkaloids, pyrrolizidine alkaloids and tropane alkaloids.
Eurofins offers state-of-the-art laboratory equipment for analytical testing. Mycotoxin testing is demanding due to the inhomogeneous distribution within the sample and the appearance of mycotoxins in trace amounts.
Our equipment encompasses various homogenizing devices for large sample sizes. As some of these methods are partly automatised, we are able to offer short turnaround times to give you a quick assessment of your raw materials. Mycotoxin Testing by Eurofins.
Relevant products Food Crops amongst others corn, wheat, rye, barley Cereals Bread and cookies Dried fruits Nuts, kernels and flours Herbs and spices Milk and dairy products Coffee, cocoa Beverages e.
Contact Us Find a Laboratory.There are over 50, different kinds of molds present. Our homes are very vulnerable to mold growth especially if there is enough moisture and humidity. However, there are only different kinds of molds that impart serious health risks and what differentiates dangerous molds from safer ones are mycotoxins. The body can be subject to mycotoxin poisoning very easily because most foods we eat have a minute mycotoxin content. These mycotoxins are excreted with urine and stool.
However, eating food which has been infected by mold gives higher chances of diseases. Mycotoxins can cause persistent headachesfatiguelung diseases such as upper respiratory tract infection and sometimes, increased exposure can also cause cancer.
During the last couple of years, the lab has been advertising urine tests for mycotoxins which are supposedly meant to tell you how much and what kind of mycotoxin is present in the body. Mycotoxins are the toxic or poisonous component present in molds. These toxins mycotoxins come into human contact through a number of ways.
Molds in our homes release spores, which if breathed, deposit mycotoxins in our body. Another path is that molds infect crops and we eat those crops. In either way, molds can deposit mycotoxins in our body through a number of ways. Meanwhile, we may not have control over it, it is always good to be sure of things. Mycotoxin testing for human beings estimates the amount the mycotoxins present in our blood and hence tells whether it is a concern or not.
Furthermore, if you live in an environment which is moist and humid, or your house is or has been water damaged at any point, it is always wise to go through a mycotoxin test. Mycotoxins can also impart some very serious health risks and hence, test for them in our bodies is an important practice for a safer living.Aflatoxin Testing using Elisa Method By Sorela Scientific East Africa.
Laboratories usually have the facility to test for mycotoxins in the human body. There are currently various methods to check for mycotoxin quantities in the body.
The blood test is one of the most successful and conventional methods to test for almost anything in the body. Testing labs collect a sample of your blood and run it for mycotoxin levels. Another method is urine testing. Urine testing is comparatively a newer and equally effective method. Some labs also collect tissue samples which can be more effective for running mycotoxins deposited by certain kinds of molds. Although urine is one way to tell about the presence of mycotoxins in the human body, it is by no means the most accurate method to make assumptions.
A cut off has not been declared that suggests what amount is too much amount in the human body and therefore, an assumption made on the basis of the amount of mycotoxin present may be flawed. Anti-fungal treatment and diseases, mold testing and removal etc. Considering this point of view, any solid assumption should not be made on the basis of a urine test.